Mandy Moore and Justin Hartley from "This Is Us" will host NBC's "Red Nose Day Special" airing Thursday, May 21 at 9:00 p.m. ET/PT.

Soap opera fans may best know actress June Squibb from her 2008-2009 stint as Katherine Chancellor’s (Jeanne Cooper) diner friend, Pearl, on “The Young and the Restless,” but the rest of the world will see her shine at this year’s Academy Awards for her role in Alexander Payne’s film, “Nebraska.”

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